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期 刊 ：中国中药杂志 1995年 20卷 12期 页码：749.

关键词：瑞香素；配合物；超氧自由基；脂质过氧化；

Keywords:daphnetin, complex, superoxide radical, lipid peroxidation,

摘 要 ：以健康人血红细胞及细胞膜为实验材料,利用核黄素-蛋氨酸光照体系产生O₂,考察了瑞香素及其铜(Ⅱ)、锌(Ⅱ)配合物对o₂的清除作用,以铜(Ⅱ)配合物活性最高。SOD、瑞香素及其铜(Ⅱ)、锌(Ⅱ)配合物对膜中过氧化脂质的产生均有一定的抑制作用。其中以SOD活性最高。

Abstract:The scavenging effects of daphnetin (D) and its Cu ,Zn complexes on superoxide radical (O₂) gener-ated through the photooxidation of riboflavin were studied with human red blood cells (RBC) and RBC membrane asexperimental material. The Cu(Ⅱ) complex showed the highest activity. SOD, D and its Cu (Ⅱ) ,Zn (Ⅱ) complexeswese found to have inhibitory effect on the production of lipid peroxide in the membrane ,SOD being the best amongthem.

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