Abstract:The baicalin in the compound recipe of traditional Chinese medicine Lung-cleaning and Diarrhoea-re-lieving Infusion was deterrmined by reverse phase high pressure liquid chromatographic method. Methanol-water-te-trahydrofuran (200 : 300 : 50) was used as the mobile phase at ODS C-18 column with ultravioet detection. The re-sult showed that baicalin was separated well from other components. Extemal standard method was used for quantita-tive determination. The recovery rate was 101.4% and RSD 0.83%.