Abstract:The contents of ursodeoxycholic acid (UDCA) and chenodeoxycholic acid (CDCA) in Chinese medicinal com-pound preparations have been determined by TLC-densitometry. The determination wavelength was 375nm and refe-rence wavelength was 700nm. For UDCA the linear range was 3.0~15.0μg and recovery was 97.2% (RSD =1.2%) . and for CDCA the linear range was 4.0~20.0μg and recovery was 99.3% (RSD=2.1% ).