Abstract:A L9(34) form developed by the orthogonal method was used to study the size,extraction solvent and extrac-tion frequency of licorice root extract,and taking the recovery of glycyrrhizic acid as the criteria,a comparison wasmade on the different ways of extracting the herb. The result showed that glycyrrhizic acid could be recovered over10%(about 7%higher than that from water treatment) when the herb was, cut into pieces and then extracted byfluxing for 3 times with 60%alcohol containing 0.3%ammonia.