Abstract:ALG is an extract from Arillus Iongan and Gecko. Our experiment has shown that ALG ig 20ml/kg/d×10 elevates significantly tolerance in mice under low and high temperatures and anoxia, and also increases the body-weight of normal mice, while ALG ig 15ml/kg/d×14 protects body-weight from decreasing in reserpinized mice. An increase in spleen-weight has also been observed in normal mice with ALG ig 20ml/kg/d×7, and ALG ig 15ml/kg/d×10 elevates the clearance rate of iv charcoal particles in normal mice.