Abstract:The experimental hepatic lesion of C67 mice was induced by carbon tetrachloride(CCl4), and the feeds containing pollen of Codonopsis pilosula were given to the animals. It was found by electronic microscopy that these pollens evidently reduced the hepatic steatosis, improved liver necrosis, suppressed the formation of the collagen fibrils in Disse‘s spaces and around central veinules, It was shown that the pollens of Codonopsis pilosula could counteract efficiently the liver lesion of mice induced by CCl4.