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期 刊 ：中国中药杂志 1989年 14卷 05期 页码：44.

关键词：自由基；脂质过氧化；衰老；人参茎叶总皂甙；人参芦头总皂甙；

Keywords:free radical, lipid peroxidation, aging, Ginseng stem leaf saponin, Ginseng rhizoma saponin,

摘 要 ：采用在体与离体二种方法研究了人参茎叶、芦头总皂甙对老年、中年大鼠肝勻浆和血清脂质过氧化的影响,实验结果表明:大鼠脂质过氧化反应随增龄而增高,两种皂甙对老、中年大鼠均有明显抑制脂质过氧化作用(P<0.05和<0.00,),并在小鼠实验中得到相同的结果。

Abstract:The effect of saponins isolated from the stem, leaf and rhizoma of panax ginseng on the formation of lipid peroxides in aged (30, 24 and 20 months) and middle-aged (14 months) wistar rats was studied with both in vivo and in vitro methods. The results showed: The formation of lipid perxides increased with age in rats and mice: the two saponins of ginseng stem, leaf and rhizoma can obviously inhibit the lipid peroxidation in the serum (plasma) and liver homogenate of aged and middle-aged rats (p<0.05 and<0.001). The same effect was also shown in the aged LACA mouse (18 months) experiment.

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