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作 者 ：高幼衡,朱盛华,魏志雄,许睿

期 刊 ：中草药 2009年

关键词：三叉苦；香豆素；三叉苦甲素；

Keywords:Evodia lepta (Spreng.)Merr., coumartn, evodosin A,

摘 要 ：目的研究三叉苦的化学成分。方法利用多种柱色谱方法进行分离纯化,根据光谱数据和理化性质进行结构鉴定。结果从三叉苦中分离出2个化合物,分别是赤式-3-(1′,2′,3′-三羟基)异戊基-7-羟基香豆素(Ⅰ)和β-胡萝卜苷(Ⅱ)。结论化合物Ⅰ是新化合物,命名为三叉苦甲素(evodosin A);化合物Ⅱ是首次从该植物中分离得到。

Abstract:Objective To study the chemical constituents of Evodia lepta.Methods The chemicalconstituents were isolated by chromatographic methods and their structures were elucidated by physico-chemical characteristics and spectral data. Results Two compounds were isolated and their structureswere identified as erythro-3-(1’，2‘，3‘-trihydroxy) isopentyl-7-hydroxycoumarin(I)and β-daucosterol(Ⅱ).Conclusion Compound I is a new one named evodosin A while compound II is isolated from E.lepta for the first time.

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