全 文 ：广 西 植 物 Guihaia　Aug．２０１５,３５(４):５６４－５６８　　　　　　　　　　 http://journal．gxzw．gxib．cn　
DOI:１０．１１９３１/guihaia．gxzw２０１３１２０３３
黄永林,李典鹏,杨子明．红背山麻杆叶的化学成分研究 (Ⅳ)———多酚类化合物[J]．广西植物,２０１５,３５(４):５６４－５６８
HuangYL,LiDP,YangZM．ChemicalconstituentsfromtheleavesofAlchorneatrewioides(４)．Polyphenols[J]．Guihaia,２０１５,３５(４):５６４－５６８
Chemicalconstituentsfromtheleavesof
Alchorneatrewioides(４)．Polyphenols
HUANGYongＧLin∗,LIDianＧPeng,YANGZiＧMing
(GuangxiKeyLaboratoryofFunctionalPhytochemicalsResearchandUtilization,
GuangxiInstituteofBotany,Guilin５４１００６,China)
Abstract:Alchorneatrewioides,asatraditionalChinesemedicine,wasusedtoaleviateilnessanddiscomfortinChiＧ
na,butthematerialbasisofpharmacodynamicwasunknown．InordertoresearchforthematerialbasisofpharmacoＧ
dynamicfromA．trewioidesleaves,thefreshleavesofA．trewioideswereextractedwith８０％aqueousacetoneand
assignedbypetroleumetherandwater．ThepetroleumetherandwaterextractsweresubjectedtothecolumnchroＧ
matographybyMCIgelCHP２０P,SephadexLHＧ２０,andToyopearlButylＧ６５０C,respectively,toyieldninepolyＧ
phenols．Theirstructureswereidentifiedbymeansof１HNMR,１３CNMR,DEPT,andcomparisonwithliterature
as:elagicacid(１),３ＧOＧmethylelagicacid(２),decarboxyelagicacid(３),１ＧOＧgaloylＧβＧDＧglucose(４),１,６ＧdiＧOＧ
galoylＧβＧDＧglucose(５),corilagin(６),phylanthusinD(７),furosonin(８),andgeranin(９),respectively．Compounds
２Ｇ９wereobtainedfromA．trewioidesforthefirsttime．
Keywords:Alchorneatrewioides;chemicalconstituents;polyphenols;elagicacid;extractionandseparation
CLCnumber:Q９４６．９１,R２８４．１　　Documentcode:A　　ArticleID:１０００Ｇ３１４２(２０１５)０４Ｇ０５６４Ｇ０５
红背山麻杆叶的化学成分研究(Ⅳ)———多酚类化合物
黄永林∗,李典鹏,杨子明
(广西植物功能物质研究与利用重点实验室,广西植物研究所,广西 桂林５４１００６)
摘　要:红背山麻杆(Alchorneatrewioides)为山麻杆属植物,作为传统的中药被用来减轻疾病和身体不适,
但它的药效物质基础尚未完全清楚.为了全面掌握红背山麻杆药效物质基础,采用８０％丙酮对其新鲜叶进
行提取,并利用 MCIgelCHP２０P、SephadexLHＧ２０等色谱柱进行分离共得到９个化合物.这些化合物的结
构经氢谱与碳谱比较分析鉴定为鞣花酸(１)、３ＧOＧ甲基没食子酸(２)、decarboxyelagicacid(３)、１ＧOＧ没食子酰
基ＧβＧDＧ葡萄糖(４)、１,６Ｇ二ＧOＧ没食子酰基ＧβＧDＧ葡萄糖(５)、柯里拉京(６)、叶下珠鞣质D(７)、furosonin(８)、老鹳
草素(９).其中化合物２~９均为首次从该属植物中分离得到.
关键词:红背山麻杆;化学成分;多酚;鞣花酸;提取与分离
　 　Alchorneatrewioides,asatraditionalChinese
medicine,wasusedtoreduceilness,discomfort,and
treatedinflammationoftheprostategland,hematuria,
andotherdiseasesinChina(JiangsuNewMedicalColＧ
lege,１９７７)．Inpreviously,thepolyphenols,suchas
flavonoids,quinicacids,phenylethanoids,andphenolＧ
收稿日期:２０１４Ｇ１２Ｇ２６　　修回日期:２０１５Ｇ０２Ｇ０９
基金项目:广西自然科学基金(２０１１GXNSFD０１８０３８);广西科技合作与交流计划项目(桂科合１２９８０１４Ｇ１０);广西植物研究所基本业务费项目(桂植业
１３００２);广西植物功能物质研究与利用重点实验室开放基金(ZRJJ２０１３Ｇ７).
作者简介:黄永林(１９７４Ｇ),男,广西桂林人,博士,研究员,主要从事天然产物物质基础、生物活性及开发利用研究,(EＧmail)hyl＠gxib．cn.
∗通讯作者
icacidshavebeenreported(Lu,２０１２;Qin,２０１２,
Huang,２０１３,２０１４,２０１５)．However,theothermain
componentsofpolyphenolshavenotbeenreported,
andthe materialbasisofpharmacodynamicisunＧ
known．InordertograspforthematerialbasisofA．
trewioides,８０％ acetoneextractsweresubjectedto
thecolumnchromatographybyMCIgelCHP２０P,
SephadexLHＧ２０,andToyopearlButylＧ６５０C,respecＧ
tively,toyieldninepolyphenols．Theirstructureswere
identifiedbymeansof１H NMR,１３CNMR,DEPT
andcomparisonwithliterature．Compounds２Ｇ９were
obtainedfromtheA．trewioidesforthefirsttime．
１　MaterialsandMethods
１HＧand１３CＧNMRspectraweremeasuredwitha
JEOLJNMＧAL４００spectrometer(Tokyo,Japan),
operatingat４００MHzfor１H,and１００MHzfor１３C,
oraBrukerAvance５００spectrometer(BrukerBiospin
AG,Faelanden,Switzerland),operatingat５００MHz
for１H,and１２５MHzfor１３C．Couplingconstantsand
chemicalshiftsweregiveninHzandonaδ(ppm)
scale,respectively．Columnchromatographywasused
onMCIgelCHP２０P,SephadexLHＧ２０andToyopearl
ButylＧ６５０C．TLCwascarriedoutonsilicagel６０F２５４
(Merck),withformicacidＧformateＧtolueneＧethyl(２∶
８∶２,or１∶７∶１v/v),andsportswerevisualized
witha２％ethanolicFeCl３．
TheleavesofAlchorneatrewioideswerecolected
intheGuilinBotanicalGarden,Guangxi,China,in
August２０１１．ThesampleplantwasidentifiedbyProf．
WEIFaＧNanofGuangxiInstituteofBotany,anda
herbariumspecimen(２０１１０９２０N)wasdepositedin
theGuangxiInstituteofBotany．
２　ExtractionandIsolation
Thesmalpieces,freshleavesof(５．３５kg)were
extractedwith８０％acetoneforthreetimes,atroom
temperature．ThefiltratewasevaporatedbyrotaryeＧ
vaporationtogiveanextract．Theextract(６１０g)was
assignedbetweenEt２O(１L)andH２O(３L)３times．
ThepartofEt２OＧsolublefraction(Fr．E５．４６g)was
dissolvedinEtOHandappliedtoaSephadexLHＧ２０
column(３．５cmi．d．×４５cm)with１００％－０EtOH
(２０％ stepwiseelution,each３００mL)togivefive
fractions．TheEＧ３(０．６７g)wasappliedtoaMCIgel
CHP２０Pcolumn(２．５cmi．d．×２５cm)withMeOHＧ
H２O(０∶１００－１００∶０)toobtain３(７０mg)．Thepart
ofwaterＧsolublefractionwasdissolvedinwaterand
appliedtoaSephadexLHＧ２０column(１０cmi．d．×４０
cm),elutingsuccessivelywithH２O,２０％,４０％,
６０％,８０％,１００％ MeOHＧH２Otoyield９fractions
(Fr．１Ｇ９)．Thefraction３(６．５１g)wasappliedbya
combinationofcolumnchromatographyoverSephadex
LHＧ２０,MCIgelCHP２０P,andToyopearlButylＧ６５０C
toobtain４(４５mg)and５(２８mg)．Fraction６(３６．０g)
wasseparatedbyMCIgelCHP２０PcolumnchromaＧ
tographytogivesevenfractions．Fraction６Ｇ４(２．４５g)
wasseparatedbyacolumnchromatographyoverSephＧ
adexLHＧ２０column(４cmi．d．×３５cm)withMeOHＧ
H２O(０∶１００)toyield６(２．１５g)．Fraction７(４３．０g)
wasappliedbya MCIgelCHP２０Pcolumnwith
MeOHＧH２O(０∶１００)toafordfivefractions．FracＧ
tion７Ｇ１wasfurtherseparatedbyMCIgelCHP２０P
andSephadexLHＧ２０columntogive６(４．５２g),８(１１６
mg)．Separationoffraction７Ｇ２usingSephadexLHＧ２０
(３cmi．d．×５０cm)withMeOHＧH２O(０∶１００－１００
∶０),andfinalywith６０％acetonetoaford７(４７６
mg)．Separationoffraction７Ｇ３usedSephadexLHＧ２０,
ChromatorexODS,andToyopearlButylＧ６５０CtoafＧ
ford１(１４mg),２(３１mg),９(６．４１g)．
３　ResultsandAnalysis
Elagicacid (１)　amorphouswhitepowder,
C１４H６O８．１HＧNMR(４００MHz,DMSO)β:７．５０(２H,
s,HＧ５,５′);１３CＧNMR(１２５MHz,DMSO)β:１０６．８
(CＧ１,１′),１０９．７(CＧ５,５′),１１２．６(CＧ６,６′),１３６．３(CＧ
２,２′),１４０．６(CＧ３,３′),１４８．１(CＧ４,４′),１５９．１(CＧ７,
７′)(Khacetal．,１９９０)．
３ＧOＧMethylelagicacid(２)　amorphouswhite
powder,C１５H８O８．１HＧNMR(５００MHz,DMSO)β:
４．０３(３H,s,３ＧOMe),７．４３(１H,s,HＧ５′),７．５０(１H,
s,HＧ５,５′);１３CＧNMR(１２５MHz,DMSO)β:６０．７(CＧ
OMe),１０７．１(CＧ６′),１１０．７(CＧ５′),１１１．６(CＧ５),１１１．９
５６５４期　　　　　　　　黄永林等:红背山麻杆叶的化学成分研究(Ⅳ)———多酚类化合物
Fig．１　Chemicalstructuresofcompounds１－９
(CＧ１),１１２．５(CＧ６),１１３．１(CＧ１′),１３７．０(CＧ２′),
１３４．０(CＧ３′),１４１．６(CＧ３),１４０．９(CＧ２),１４８．１(CＧ
４′),１５２．２(CＧ４),１５８．６(CＧ７′),１５８．８(CＧ７)(Baiet
al．,２００８)．
Decarboxyelagicacid(３)　amorphouswhite
powder,C１３H８O７．１HＧNMR(４００MHz,CD３OD)
β:６．７３(１H,d,J＝８．１Hz,HＧ５′),７．４１(１H,s,
HＧ５),８．４２(１H,d,J＝８．１Hz,HＧ６′);１３CＧNMR
(１００MHz,CD３OD)β:１０８．１(CＧ５),１１２．１(CＧ６),
１１２．４(CＧ５′),１１２．８(CＧ１′),１１８．５(CＧ１),１１９．１(CＧ
６′),１３３．３(CＧ３′),１４１．１(CＧ３),１４１．８(CＧ２′),１４４．０
(CＧ２),１４６．４(CＧ４),１４６．８(CＧ４′),１６３．８(CＧ６)
(Pfundsteinetal．,２０１０)．
１ＧOＧGaloylＧβＧDＧglucose (４)　 amorphous
brownpowder,C１３H１６O１０．１HＧNMR(５００MHz,
acetoneＧd６)β:３．１８(１H,t,J＝８．８Hz,HＧ４),
６６５ 广　西　植　物　　　 　　　　　　　　　　　　　　３５卷
３．２１Ｇ３．５５(３H,m,HＧ２,３,５),３．４６(１H,dd,J＝
６．１,１２．０Hz,HＧ６ax),３．６４(１H,dd,J＝３．９,
１２．０Hz,HＧ６eq),５．５３(１H,d,J＝８．５Hz,HＧ１),
７．２３(２H,s,HＧ２′,６′);１３CＧNMR(１２５MHz,aceＧ
toneＧd６)β:６０．３(CＧ６),６９．６(CＧ４),７２．３(CＧ２),
７５．６(CＧ５),７６．１(CＧ３),９３．４(CＧ１),１０８．９(２C,CＧ
２′,６′),１１９．４(CＧ１′),１３７．０(CＧ４′),１４４．０(２C,CＧ
３′,５′),１６５．２(CＧ７′)(ElＧEkkawyetal．,１９９５)．
１,６ＧDiＧOＧgaloylＧβＧDＧglucose(５)　amorphous
brownpowder,C２０H２０O１４．１HＧNMR(５００MHz,
acetoneＧd６)β:３．２１Ｇ３．７５(４H,m,HＧ２,３,４,５),
４．４２(１H,dd,J＝６．５,１２．０Hz,HＧ６ax),４．５８
(１H,dd,J＝２．７,１２．０Hz,HＧ６eq),５．６７(１H,d,
J＝７．５Hz,HＧ１),７．０８,７．１５(each２H,s,HＧ２′,
６′and２″,６″);１３CＧNMR(１２５MHz,acetoneＧd６)β:
６３．３(CＧ６),７０．３(CＧ４),７３．６(CＧ２),７５．１(CＧ５),
７６．８(CＧ３),９５．７(CＧ１),１０７．９,１０８．０(each２C,CＧ
２′,６′and２′,６″),１１９．３,１１９．４(CＧ１′,１″),１３６．９,
１３７．４(CＧ４′,４″),１４３．９,１４４．０(each２C,CＧ３′,５′
and３″,５″),１６５．１,１６５．１(CＧ７′,７″)(Yanetal．,
２００７)．
Corilagin(６)　amorphousbrownpowder,
C２７H２２O１８．１HＧNMR(５００ MHz,acetoneＧd６)β:
４．０８(１H,brs,HＧ２),４．１３(１H,dd,J＝８．５,１１．０
Hz,HＧ６ax),４．４６(１H,brs,HＧ４),４．５２(１H,t,
J＝８．５Hz,HＧ５),４．８３(１H,brs,HＧ３),４．９１
(１H,t,J＝１１．０Hz,HＧ６eq),６．３８(１H,s,HＧ１),
６．７０(１H,s,HＧringBＧ５),６．８４(１H,s,HＧringCＧ
５),７．１２(２H,s,HＧringAＧ２,６);１３CＧNMR(１２５
MHz,acetoneＧd６)β:６１．３(CＧ４),６３．５(CＧ６),６８．１
(CＧ２),６９．９(CＧ３),７４．７(CＧ５),９３．５(CＧ１),１０７．１
(CＧringBＧ５),１０９．１(CＧringCＧ５),１０９．８(２C,CＧ
ringAＧ２,６),１１５．１(CＧringBＧ１),１１５．８(CＧringCＧ
１),１１９．８(CＧringAＧ１),１２４．７(CＧringCＧ２),１２４．８
(CＧringBＧ２),１３５．７(CＧringCＧ３),１３６．３(CＧringBＧ
３),１３８．５(CＧringAＧ４),１４３．９(CＧringCＧ４),１４４．０
(CＧringBＧ４),１４４．１(CＧringCＧ６),１４４．５(CＧringBＧ
６),１４５．０(２C,CＧringAＧ３,５),１６４．６(CＧringAＧ
７),１６６．５(CＧringCＧ６),１６７．９(CＧringBＧ７)(Chung
etal．,２００３;Thitilertdechaetal．,２０１０)．
Phylanthusin D (７)　amorphousbrown
powder,C４４H３２O２７．１HＧNMR(５００MHz,acetoneＧ
d６)β:２．１９(３H,s,HＧringEＧ９′),２．９８(１H,d,J
＝１５．５Hz,HＧringEＧ７ax′),３．４７(１H,d,J＝１５．５
Hz,HＧringEＧ７eq′),４．４０(１H,dd,J＝７．５,１０．０
Hz,HＧ６ax),４．７８(１H,t,J＝７．５Hz,HＧ６eq),
４．８１(１H,t,J＝７．５Hz,HＧ５),４．９１(１H,brs,HＧ
ringEＧ１′),５．４３(１H,brs,HＧ４),５．５３(１H,brs,
HＧ３),５．５６(１H,brs,HＧ２),６．３０(１H,s,HＧring
EＧ３′),６．５７(１H,brs,HＧglcＧ１),６．６５(１H,s,HＧ
ringBＧ３),７．０７(１H,s,HＧringCＧ３),７．１７(２H,s,
HＧringAＧ２,６),７．２３(１H,s,HＧringDＧ３);１３CＧ
NMR(１２５ MHz,acetoneＧd６)β:３１．０(CＧringEＧ
９′),４９．１(CＧringEＧ７′),５１．１(CＧringEＧ１′),６１．５
(CＧ３),６３．０(CＧ６),６５．８(CＧ４),６９．５(CＧ２),７２．３(CＧ
５),８０．０(CＧringEＧ５′),９１．０(CＧ１),１０７．０(CＧringCＧ
３),１０８．８(CＧringEＧ６′),１０９．５(CＧringBＧ３),１０９．８
(２C,CＧringAＧ２,６),１１２．５(CＧringDＧ３),１１４．５(CＧ
ringCＧ１),１１６．０(CＧringDＧ１),１１６．４(CＧringCＧ１),
１１９．３(CＧringAＧ１),１１９．３(CＧringDＧ２),１２３．５(CＧ
ringBＧ２),１２４．５(CＧringCＧ２),１２６．０(CＧringEＧ３),
１３５．６(CＧringCＧ５),１３６．５(CＧringDＧ５),１３６．９(CＧ
ringBＧ５),１３９．６(CＧringAＧ４),１４３．８(CＧringBＧ４),
１４４．１(CＧringBＧ６),１４４．４(CＧringCＧ６),１４４．６(CＧ
ringCＧ４),１４４．７(CＧringEＧ２′),１４５．２(２C,CＧring
AＧ３,５),１４６．１(CＧringDＧ６),１４６．８(CＧringDＧ４),
１６３．９(CＧringEＧ１０′),１６４．３(CＧringDＧ７),１６４．６(CＧ
ringAＧ７),１６５．４(CＧringBＧ７),１６７．７(CＧringCＧ７),
１９６．８(CＧringEＧ４′),２０５．３(CＧringEＧ８′)(Fooet
al．,１９９２;Yoshindetal．,１９９２)．
Furosonin(８)　amorphousbrownpowder,
C４６H３６O３１．１HＧNMR(５００ MHz,acetoneＧd６)β:
１．６３(１H,d,J＝１４．０Hz,HＧringEＧ３ax),２．７３
(１H,d,J＝１４．０Hz,HＧringEＧ３eq),３．９３(１H,
dd,J＝２．５,９．５Hz,HＧringFＧ１ax),４．０９(１H,m,
HＧringFＧ２),４．１２(１H,dd,J＝５．５,９．５Hz,HＧ
ringFＧ１eq),４．１６(１H,d,J＝１．５Hz,HＧringFＧ
３),４．４４(１H,t,J＝１０．０Hz,HＧ６ax),４．７３(１H,
m,HＧ６eq),４．７５(１H,s,HＧringEＧ１),４．９１(１H,
t,J＝９．０Hz,HＧ５),５．０５(１H,s,HＧringFＧ５),
５．３６(１H,brs,HＧ４),５．６１(１H,brs,HＧ２),５．６６
(１H,brs,HＧ３),６．５３(１H,brs,HＧ１),６．６４
(１H,s,HＧringBＧ３),７．０７(１H,s,HＧringCＧ３),
７．２１(２H,s,HＧringAＧ２,６),７．３３(１H,s,HＧring
DＧ３);１３CＧNMR(１２５MHz,acetoneＧd６)β:３１．６(CＧ
ringEＧ３),５１．２(CＧringEＧ１),５２．５(CＧringEＧ２),
７６５４期　　　　　　　　黄永林等:红背山麻杆叶的化学成分研究(Ⅳ)———多酚类化合物
６２．１(CＧ３),６３．２(CＧ６),６５．４(CＧ４),６９．７(CＧ２),
７２．６(CＧ５),７４．４(CＧringFＧ１),７６．４(CＧringFＧ５),
７６．５(CＧringFＧ２),８０．７(CＧringFＧ３),９０．９(CＧ１),
９７．７(CＧringEＧ４),９８．１(CＧringEＧ６),９８．２(CＧring
EＧ５),１０６．８(CＧringCＧ３),１０８．９(CＧringFＧ４),
１０９．６(CＧringCＧ３),１０９．８(２C,CＧringAＧ２,６),
１１０．６(CＧringDＧ１),１１３．９(CＧringDＧ３),１１４．８(CＧ
ringBＧ１),１１６．３(CＧringCＧ１),１１８．３(CＧringDＧ２),
１１９．０(CＧringAＧ１),１２３．５(CＧringBＧ２),１２４．６(CＧ
ringCＧ２),１３５．６(CＧringBＧ５),１３７．１(CＧringCＧ５),
１３８．１(CＧringDＧ５),１３９．４(CＧringAＧ４),１４４．０(CＧ
ringBＧ４),１４４．１(CＧringCＧ４),１４４．４(CＧringDＧ６),
１４４．５(CＧringBＧ６),１４４．７(CＧringCＧ６),１４５．１(CＧ
ringDＧ４),１４５．２(２C,CＧringAＧ３,５),１６４．７(CＧ
ringBＧ７),１６５．１(CＧringDＧ７),１６５．８(CＧringAＧ７),
１６８．１(CＧringCＧ７),１６９．９(CＧringEＧ７)(Taniguchi
etal．,２０１２)．
Geranin (９)　amorphousbrownpowder,
C４１H２８O２７．１HＧNMR(５００ MHz,acetoneＧd６)β:
４．３３[１H,dd,J＝６．０,１０．５Hz,H(a)Ｇ６ax],４．４４
[１H,dd,J＝８．０,１０．５Hz,H(b)Ｇ６ax],４．７６
[１H,d,J＝１．６Hz,H(b)ＧringEＧ１′],４．８０[１H,
m,H(a)Ｇ５],４．８０[１H,m,H(b)Ｇ５],４．９１[１H,
m,H(b)Ｇ６eq],４．９４[１H,t,J＝１０．５Hz,H(a)Ｇ
６eq],５．１９[１H,s,H(a)ＧringEＧ１′],５．５４[１H,
brs,H(a)Ｇ４],５．４４[１H,brs,H(b)Ｇ４],５．５０
[１H,brs,H(a)Ｇ３],５．５７[１H,brs,H(b)Ｇ３],
５．５８[１H,brs,H(a)Ｇ２],５．５８[１H,brs,H(b)Ｇ
２],６．２７[１H,d,J＝１．６Hz,H(b)ＧringEＧ３′],
６．５４[１H,brs,H(b)Ｇ１],６．５８[１H,s,H(a)Ｇ１],
６．５８[１H,s,H(a)ＧringEＧ３′],６．６７[１H,s,H
(b)ＧringCＧ３],６．６８[１H,s,H(a)ＧringCＧ３],７．１０
[１H,s,H(b)ＧringBＧ３],７．１６[１H,s,H(a)Ｇring
BＧ３],７．２１[２H,s,H(a)ＧringAＧ２,６],７．２１[２H,
s,H(b)ＧringAＧ２,６],７．２３[１H,s,H(a)ＧringDＧ
３],７．２７[１H,s,H(b)ＧringDＧ３];１３CＧNMR(１２５
MHz,acetoneＧd６)β:４６．２[C(a)ＧringEＧ１′],５２．０
[C(b)ＧringEＧ１′],６２．５[C(b)Ｇ３],６３．８[C(a)Ｇ６],
６３．８[C(b)Ｇ６],６３．９[C(a)Ｇ３],６５．９[C(a)Ｇ４],
６６．０[C(b)Ｇ４],７０．２[C(a)Ｇ２],７０．６[C(b)Ｇ２],
７２．７[C(a)Ｇ５],７３．３[C(b)Ｇ５],９０．９[C(a)Ｇ１],
９１．８[C(b)Ｇ１],９１．９[C(b)ＧringEＧ５′],９１．９[C
(b)ＧringEＧ６′],９２．４[C(a)ＧringEＧ６′],９６．３[C
(a)ＧringEＧ５′],１０７．９[C(b)ＧringCＧ３],１０８．０[C
(a)ＧringCＧ３],１０９．８[C(b)ＧringBＧ３],１１０．６[C
(a)ＧringBＧ３],１１０．７ [２C,C(b)ＧringAＧ２,６],
１１０．９[２C,C(a)ＧringAＧ２,６],１１３．４[C(b)Ｇring
DＧ３],１１３．５[C(a)ＧringDＧ３],１１５．２[C(b)ＧringCＧ
１],１１５．３[C(a)ＧringCＧ１],１１５．９[C(a)ＧringDＧ
１],１１７．０[C(b)ＧringBＧ１],１１７．１[C(b)ＧringDＧ
２],１１７．２[C(a)ＧringBＧ１],１１９．５[C(a)ＧringDＧ
２],１２０．１[C(b)ＧringAＧ１],１２０．２[C(b)ＧringDＧ
１],１２０．７[C(a)ＧringAＧ１],１２４．７[C(b)ＧringBＧ
２],１２４．８[C(a)ＧringBＧ２],１２５．１[C(b)ＧringEＧ
３′],１２５．５[C(b)ＧringCＧ２],１２５．７[C(a)ＧringCＧ
２],１２８．７[C(a)ＧringEＧ３′],１３６．４[C(b)ＧringCＧ
５],１３６．５[C(a)ＧringCＧ５],１３７．２[C(b)ＧringDＧ
５],１３７．７[C(b)ＧringBＧ５],１３７．８[C(a)ＧringBＧ
５],１３９．０[C(a)ＧringDＧ５],１３９．９[C(a)ＧringAＧ
４],１４０．０[C(b)ＧringAＧ４],１４３．５[C(a)ＧringDＧ
６],１４４．６[C(b)ＧringBＧ４],１４４．９[C(a)ＧringCＧ
６],１４４．９[C(b)ＧringBＧ６],１４５．０[C(a)ＧringBＧ
６],１４５．２[C(b)ＧringCＧ６],１４５．３[C(a)ＧringBＧ
４],１４５．４[C(b)ＧringCＧ４],１４５．５[C(a)ＧringCＧ
４],１４５．８[C(a)ＧringDＧ４],１４５．９[２C,C(a)Ｇring
AＧ３,５],１４５．９[２C,C(b)ＧringAＧ３,５],１４７．０[C
(b)ＧringDＧ６],１４７．６[C(b)ＧringDＧ４],１４９．３[C
(b)ＧringEＧ２′],１５４．７[C(a)ＧringEＧ２′],１６４．７[C
(a)ＧringAＧ７],１６４．９[C(b)ＧringAＧ７],１６５．４[C
(b)ＧringDＧ７],１６５．５[C(a)ＧringDＧ７],１６５．６[C
(a)ＧringEＧ７′],１６５．８[C(b)ＧringBＧ７],１６５．９[C
(b)ＧringEＧ７′],１６６．２[C(a)ＧringBＧ７],１６８．４[C
(b)ＧringCＧ７],１６８．５[C(a)ＧringCＧ７],１９４．６[C
(b)ＧringEＧ４′],１９１．９[C(a)ＧringEＧ４′](Yoshindet
al．,１９９２)．
References:
BaiN,HeK,RolerM,etal．２００８．ActivecompoundsfromLagerＧ
stroemiaspeciosa,insulinＧlikeglucoseuptakeＧstimulatory/inhibiＧ
toryandadipocytediferentiationＧinhibitoryactivitiesin３T３ＧL１
cels[J]．JAgricFoodChem,５６(２４):１１６６８－１１６７４
ChungSK,NamJA,JeonSY,etal．２００３．AprolylendopeptiＧ
daseＧlnhibitingantioxidantfrom Phyllanthusussurensis[J]．
ArchPharmRes,２６(１２):１０２４－１０２８
EditorialCommitteeinFloraofChina．１９９６．FloraofChina．FasciＧ
cule２．[M]．Beijing:SciencePress,４４:６６－７４
FooLY,WongH．１９９２．PhylanthusinD,anunusualhydrolysＧ
abletanninfromPhyllanthusamarus[J]．Phytochemistry,３１
(下转第５３８页Continueonpage５３８)
８６５ 广　西　植　物　　　 　　　　　　　　　　　　　　３５卷