Abstract:The chemical constituents of the root of GlYcyrrhiza aspera Pall. collected in Xinjiang Autonomous Region of China were studied. Seven compounds were isolated and identified, They are glycyrrhizic acid, liquiritin, isoliquiritin, glycycoumarin, isoglycycoumarin, glycyrol and isoglycyrol. The structures of these compounds were elucidated by spectroscopic methods and chemical transformation. They were all isolated from G. aspera for the first time, among them isoglycycoumarin is a new compound, its structure was proved to be 3-(2’,4’-dihydro-xyphenyl), 5-methoxyl, 6,7-(6’,6’-dimethyl pyrano) coumarin.