Abstract:A diterpenoid having ent-kaurene-skeleton, ttenryine A, has been isotated front the ethanol extract of Rabdosia henryi (Hemsl) Hara (Labiata) leaves collected in west Hubei. The structure of henryine A was determined as ent-7α, 14β-dihyd-roxy-19α-hydroxymethyl-Kaur-16-en-ll, 15-dione(Ⅰ) by means of spectroscopic analysis. This compound of diterpenoid was shown to have inhibitory action on Hela cells and staphylococcus aureus, et al in vitro.