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期 刊 ：中国中药杂志 2007年 32卷 08期 页码：692.

关键词：红厚壳；黄酮类化合物；

Keywords:Calophyllum inophyllum, flavonoids,

摘 要 ：目的：研究红厚壳茎叶的化学成分。方法：利用硅胶柱色谱,Sephadex LH-20柱色谱,PTLC等手段进行化合物的分离,运用¹H,¹³C,2D-NMR,MS等波谱分析法确定结构。结果：分离并鉴定了9个黄酮类化合物,分别为：2-羟基酮(1),4-羟基酮(2),1,5-二羟基酮(3),1,7-二羟基酮(4),1,3,5-三羟基-2-甲氧基酮(5),6-deoxyjacareubin(6),穗花杉双黄酮(7),山柰酚-3-O-α-L-鼠李糖苷(8),槲皮苷(9)。结论：化合物8和9为首次从红厚壳属植物中得到,化合物1,2,4～6为首次从该植物中得到。

Abstract:Objective: To study the chemical constituents from the stems and leaves of Calophyllum inophyllum. Method: The compounds were isolated by column chromatography on silica gel, Sephadex LH-20 and preparative TLC. Their structures were elucidated by chemical methods and NMR, MS spectroscopic data. Result: Nine compounds were identified as 2-hydroxyxanthone (1), 4-hydroxyxanthone (2), 1, 5-dihydroxyxanthone (3), 1, 7-dihydroxyxanthone (4), 1, 3, 5-trihydroxy-2-methoxyxanthone (5), 6-deoxyjacareubin (6), amentoflavone (7), kaempferol-3-O-α-L-rhamnoside (8) and quercetin-3-O-α-L-rhamnoside (9). Conclusion: Compounds 8 and 9 were isolated from the genus Calophyllum and compounds 1, 2, 4-6 were isolated from this plant for the first time.

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