Abstract:To further understand sinomenine,this paper has introduced the abstract technology,assaying,pharmaceutical chemistry,pharmacological action,pharmacotoxicology,pharmacokinetics and clinical application of sinomenine based on the important and significant contents of reference which have been consulted in the past ten years.Sinomenine is a kind of non-steroidal anti-inflammatory drugs with very effective and little side effect and expected it as a good new drug withdrawal medicine in the future.