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期 刊 ：中国中药杂志 2005年 30卷 16期 页码：1263.

关键词：草泽泻；三萜；化学成分；

Keywords:Alisma gramineum, triterpenes, chemical constituents,

摘 要 ：目的:研究草泽泻三萜类化学成分。方法:利用硅胶柱色谱和HPLC色谱进行分离纯化,运用NMR,MS,IR等光谱手段进行结构鉴定。结果:分离得到了5个原萜烷型四环三萜类化合物,分别为:16,23-氧化泽泻醇B(1),11-去氧泽泻醇C(2),泽泻醇F(3),16β-甲氧基泽泻醇B单乙酯(4),16β-羟基泽泻醇B单乙酯(5)。结论:所有化合物均为首次从该植物中分离得到。

Abstract:Objective: To investigate the triterpenoids chemical constituents in rhizome of Alisma gramineum. Method: Silicon gel chromatography and HPLC techniques were employed for isolation and purification of the constituents, and the structures were elucidated by various spectral analyses such as NMR, MS and IR. Result: 5 protostane-type tetracyclic triterpenoids were isolated and identified as 16,23-oxidoalisol B(1) , 11-deoxyalisol C(2) , alisol F(3) , 16β-methoxyalisol B acetate (4) , 16β-hydroxyalisol B acetate (5) . Conclusion: All of these compounds were found from A. gramineum for the first time.

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