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期 刊 ：中国中药杂志 1993年 18卷 07期 页码：415.

关键词：六神丸；β-环糊精；稳定性；刺激性；体外溶出；

Keywords:Liushen Pills, β-cyclodextrin, stability, irritative effect, in vitro dissolution,

摘 要 ：经质量检查、稳定性试验、刺激性试验和体外溶出试验结果表明:用β-环糊精包合物制备的01号六神丸较好地保存了挥发性的冰片,减轻了蟾酥的刺激性,且体外溶出较快,优于按原工艺制备的02号六神丸。

Abstract:01 Liushen Pills (prepared by β-CD inclusion complex) and 02 Liushen Pills (prepared according to the normal way) were compared by quality inspection, stability test, pharmacological experiments of irritative effects and dissolution test. The results indicated that 01 Liushen Pills were superior to 02 Liushen Pills.

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