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期 刊 ：中国中药杂志 2003年 28卷 02期 页码：147.

关键词：气质联用；五虎汤；尿液；挥发性成分；

Keywords:GC-MS, Wu-Hu-Tang, urine, volatile components.,

摘 要 ：目的:研究中药复方“五虎汤”大鼠灌胃后尿中的挥发性成分。方法:采用气质联用的方法对大鼠给药前后的尿液进行分析。结果:在给药大鼠的尿液中检测到18个与空白尿液相区别的成分,鉴定了14个,其中的7个成分在复方中也同时检测到。结论:检测到的区别成分可能来源于中药五虎汤,其中的一些成分与中药五虎汤的药效相关。

Abstract:Objective: To identify the volatile components in rat urine after oral administration of "Wu-Hu-Tang"(WHT). Method: GC-MS technique was applied to analyzing urine samples. Result: Eighteen components were detected in the WHT-treated rat urine other than the corresponding control. Among them, 14 components were identified, and 7 were also found in the extract of WHT. Conclusion: The above detected components might be derived from WHT, and some of them are effective components of WHT.

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