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期 刊 ：中国中药杂志 2005年 30卷 11期 页码：808.

关键词：毛脉酸模；采收期；主成分分析法；HPLC；

Keywords:Rumex gmelini, harvesting time, principal component analysis, HPLC,

摘 要 ：目的:分析不同生长发育期毛脉酸模中生物活性成分形成和积累规律,探索毛脉酸模采收期的选优方法,以确定最佳采收期。方法:采用HPLC,梯度洗脱,测定了2年生毛脉酸模不同生长发育期根中7种生物活性成分(白藜芦醇、白藜芦醇苷、大黄酚苷、酸模素、大黄素、大黄酚、大黄素甲醚)含量,对其进行主成分分析。结果:不同生长发育期采集的毛脉酸模中生物活性成分积累具有一定规律。结论:兼顾不同的治疗目的和含量因素,毛脉酸模的采收期以7月初为最佳。

Abstract:Objective: To establish a method used for optimization of harvesting time and determine the best time for harvesting Rumex gmelini. Method: An HPLC method was applied to determinate the contents of seven active constituents(resveratrol, polydatin, chrysophanol 1-glucoside, nepodin, emodin, chrysophanol and physcion)of R. gmelini at different development stage. The result was analyzed by principal component analysis. Result: The accumulation of active constituents showed a regular pattern. Conclusion: The best harvesting time of R. gmelini is early July.

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