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期 刊 ：中国中药杂志 1999年 24卷 05期 页码：291.

关键词：大黄；煎煮；蒽醌；化学变化；

Keywords:Radix et Rhizoma Rhei, decocting, anthraquinone, chemical change,

摘 要 ：目的：了解大黄煎煮过程中的化学变化。方法：采用ＨＰＬＣ法对大黄煎煮前后生药、煎液及药渣中的各种蒽醌的含量进行监测。结果：生药煎煮后各种结合蒽醌和游离蒽醌的含量均发生了变化。结论：这种现象可能与结合蒽醌的水解，游离蒽醌的降解以及蒽醌间的相互转化有关。

Abstract:Objective:To understand the chemical changes in the decocting process of Radix et Rhizoma Rhei.Method:Comparing the contents of many kinds of anthraquinones in the crude drug, decoction and drug sediments of Radix et Rhizoma Rhei by HPLC.Result:The contents of combined and free anthraquinones changed after the crude drug was decocted.Conclusion:These changes may be related to the hydrolysis of combined anthraquinones, the decomposition of free anthraquinones, and the inter transition among anthraquinones.

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