期 刊 ：中国中药杂志 1992年 17卷 07期 页码：424.
关键词：青藤碱；高效液相色谱；药代动力学；
Keywords:sinomenine, HPLC, pharmacokinetics,
摘 要 ：用反相高效液相色谱外标法,测定单剂量(20mg/kg)静脉注射青藤碱后不同时间兔体内血药浓度,并用Marguardt法迭代拟合,结果符合二室模型。
Abstract:Pharmacokinetics of sinomenine in rabbit was studied by reverse-phase HPLC method. After iv injection of 20mg/kg of sinomenine to rabbits, the pharmacokinetic characteristics were found to fit a two-compartment open model.
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