Abstract:Rhizoma Pinelliae boiled with ginger juice has less stimulation and toxicity on animals, which is similar to Rhi- zoma Pinelliae processed by alum solution. The effect of Rhizoma Pineiliae that has been immersed in ginger juice is not as good as that of the ginger-boiled. It was also observed that the stimulation of raw Rhizoma Pinelliae on mice could be reduced when the mice was given fresh or boiled ginger juice. The Rhizoma Pinelliae processed by ginger juice and alum has very little toxicity on mice.