Abstract:This paper indicates that Paecilomyces sinensis ig 3g/kg/dx14 increases the amount of superoxide dismutase in the liver tissues of mice; that Paecilomyces sinensis is similar to natural Cordyceps sinansis in inhibiting the production of Lpo and increasing the amount of superoxide dismutase in the liver homogenates of mice in vitro. In addition Paecilomyces sinensis can also increase the amount of glutathione peroxidase in the liver homogenates of mice in vitro.