Abstract:The compound membrane of traditional Chinese medicine for mouth ulcer, which is made of drug-containing membrane and covering membrane, is a new type of preparation of traditional Chinese medicine. The comparison of different prescriptions and membrane materials in the preparation, adhesion and drug release of the membrane has shown that PVA17-88-CMCNa(1:1) and PVA17-88 act best as the base of drug-containing membrane and covering membrane material respectively.