Abstract:It has shown that alkaloid accumulation in tissue cultures of Corydalis yanhusuo orchestrated to some extent the growth in cultures. Some alkaloids, such as tetrahyclropalmatine continued to increase in the static phase of culture growth. The culture solution of Armillaria mellea as an elicitor was able to promote alkaloids accumulation in cultures, as, for example, protopine was increased up to 0.114% DW. by the eliciting but remained at trace level in cultures without elicitor.