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作 者 ：范利荣,史海明,李晓波

期 刊 ：中国中药杂志 2011年 36卷 15期 页码：2021.

关键词：人参皂苷；体外模拟代谢；人工胃液；肠道菌代谢；微生物转化；酶转化；

Keywords:ginsenoside, metabolism in vitro, artifical juice, intestinal bacteria metabolism, microbial biotransformation, enzymatic biotransformation,

摘 要 ：人参系传统名贵中药,近年来对其代谢的研究成为热点。通过查阅国内外相关文献,作者主要从人工胃液、肠道菌代谢、酶和微生物体外转化4个方面对人参皂苷体外模拟代谢及转化进行阐述,分析人参皂苷体外代谢的主要途径,为人参皂苷代谢的系统性研究提供参考。

Abstract:As a famous traditional Chinese medicine, ginseng‘s metabolism has been a hot spot in recent years. In this review, relevant literatures on the research progress of the metabolism of ginsenosides in vitro have been introduced. This review focuses on artifical juice metabolism, intestinal bacteria metabolism, microbial and enzymatic biotransformation of ginsenosides. Main metabolic pathways of ginsenosides in vitro are also analyzed, which will provide a reference for the systematic study on metabolism of ginsenosides.

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